Once you have your binary file you have two choices depending on if the game will be for cassette or disc.
[[Atari|Atari ST]] was a common 16 bit computer actually used in Cross development of games on CPC. Of course nowaday's Cross development use far more powerfull modern computers.
[[ZX Spectrum]] was also a source of Cross development...er... let's say [[Speccy Port|Gross Development]] indeed.